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isoniazid will raise the level or result of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Keep away from coadministration of pazopanib with solid CYP3A4 inhibitors if at all possible; if must coadminister, reduce pazopanib dose to four hundred mg/working dayStay away from or Use Alternate Drug. Steer clear